Red Pill
When failure isn't an option
Powerful 20mg Tadalafil dose for peak moments
Enhanced with 70mg Pycnogenol for circulation
Up to 36 hours of readiness
Starts as low as $5.39/dose*
*As shown in studies of sublingual sildenafil and apomorphine. Price shown with 3 month shipping option.
Prescription products require an online consultation with a healthcare provider. The featured products include compounded products which have not been approved by the FDA. The FDA does not verify the safety or effectiveness of compounded drugs.
When Performance Can't Be Left to Chance
Because some moments define you
Reliability When It Counts
First date after divorce. Anniversary weekend. Moment of truth with someone new. You don't get second chances. Red Pill removes the question mark.
Extended Window, Zero Anxiety
36-hour effectiveness means no clock-watching, no performance pressure, no awkward timing. Take it Friday, be ready through Sunday. Simple.
Clinical Strength You Can Feel
This isn't maintenance therapy. It's maximum-strength intervention for the moments that matter. You'll know it's working. So will your partner.
BACKGROUND AND HISTORY
The Science of Certainty
When research meets real-world results
Tadalafil 20mg shows 81% efficacy in clinical trials—among the highest success rates in ED treatment
Pycnogenol increases nitric oxide by 23% and improves erectile function scores by 45-58% in studies
Combined therapy (PDE-5 + Pycnogenol) demonstrates superior outcomes vs. monotherapy in resistant cases
36-hour half-life eliminates timing stress while maintaining peak efficacy during the critical window
Proven Performance
81%
Success rate in trials
36 hrs
Extended effectiveness
45%
Boost from Pycnogenol
8k+
Men trust Red Pill
Why Tadalafil + Pycnogenol?
Two mechanisms, one goal: unwavering performance
Tadalafil blocks PDE-5, the enzyme that breaks down cGMP—the molecule responsible for vasodilation and blood flow. More cGMP = better blood flow = stronger, more reliable erections. At 20mg, you're getting the clinical maximum.
But here's where Red Pill goes further: Pycnogenol boosts nitric oxide production upstream of the PDE-5 pathway. More nitric oxide = more cGMP production. So while Tadalafil prevents breakdown, Pycnogenol increases production. You're attacking the problem from both angles.
Studies on combination therapy show 92.5% of men with moderate ED responded to Pycnogenol + PDE-5 inhibitors vs. 45% on PDE-5 alone. The synergy isn't theoretical—it's measurable, repeatable, and clinically significant.
Red Pill isn't for daily use. It's your insurance policy for the times when "good enough" isn't acceptable.
Why Choose OnyxMD?
See what some of our customers have to say.
So grateful to have finally found a viable solution for my challenges. A bit on the pricey side but worth every penny.
Dan
It has changed life in the bedroom and dramatically improved my relationship with my wife!
Merrill
Amazing stuff, first it works...but APO really does enhance things in an incredible way.
Navaf
The combination of medicines is just right for my sexual experience. My partner is pleased too.
Don
My sex life has NEVER been as good... It's like the fountain of youth in a melt!
Michael
So grateful to have finally found a viable solution for my challenges. A bit on the pricey side but worth every penny.
Dan
How it works
Complete Medical Assessment
Answer health questions. Physician reviews your profile. No office visit.
Fast, Discreet Delivery
Prescription filled and shipped directly to your door. Plain packaging.
Take With Confidence
One pill, 30-60 minutes before. Then relax. You're covered for 36 hours.
Science-backed results
We analyzed 200+ peer-reviewed studies to bring you evidence-based therapy. Here's what the research proves.
1Brock GB, et al, "Efficacy and safety of tadalafil 20mg for erectile dysfunction: integrated analysis", Journal of Urology 2002. | https://doi.org/10.1016/S0022-5347(05)64442-4 |
2Stanislavov R, et al, "Treatment of erectile dysfunction with pycnogenol and L-arginine", Journal of Sex & Marital Therapy 2003. | https://doi.org/10.1080/713847101 |
3Ledda A, et al, "Investigation of a complex plant extract for ED: randomized, double-blind study", BJU International 2010. | https://doi.org/10.1111/j.1464-410X.2009.08791.x |
4Aizawa K, et al, "Improvement of endothelial function by Pycnogenol in patients with coronary artery disease", Journal of Cardiovascular Pharmacology 2012. | https://doi.org/10.1097/FJC.0b013e318237d122 |